Zygote

Written by Zayn Miah & R KhanomLast updated 17 September 2026Not clinically reviewed

The single cell formed immediately after a sperm fertilises an egg, before it begins dividing.

In plain English

It's the very first stage after fertilisation, a single cell, before it starts dividing into what becomes an embryo.

Why it matters

Embryologists check for this stage the day after egg collection, looking for signs of normal fertilisation.

Related terms

Guides that cover this

Written by patients, not clinicians. This page has not yet been reviewed by a named fertility professional, so it explains published guidance and points you to the original source instead of giving medical advice. It is not medical advice. Decisions about your treatment belong with your own clinic. Read our editorial policy and corrections policy.